Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.97 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.97 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.97 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.97 |
| ▸ | HTR1A | P08908 | 1/20 | 0.97 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.97 |
| ▸ | DRD1 | P21728 | 1/20 | 0.97 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.97 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.97 |
| ▸ | DRD3 | P35462 | 1/20 | 0.97 |
| ▸ | DHFR | P00374 | 1/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tretoquinol SCHEMBL249002 | 0.99 | TBXA2R (1.00) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| Tretoquinol SCHEMBL29383882 | 0.99 | TBXA2R (1.00) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| Tretoquinol SCHEMBL249003 | 0.99 | TBXA2R (1.00) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| Tretoquinol SCHEMBL1630263 | 0.97 | TBXA2R (0.97) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| Tretoquinol SCHEMBL29966739 | 0.97 | TBXA2R (0.97) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| Tretoquinol SCHEMBL1604695 | 0.97 | TBXA2R (0.97) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| Tretoquinol SCHEMBL30537714 | 0.97 | TBXA2R (0.97) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| Tretoquinol SCHEMBL11040376 | 0.96 | TBXA2R (0.95) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL12635396 | 0.88 | ADRB2 (0.80) | TBXA2RADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL17713983 | 0.88 | ADRB2 (0.80) | TBXA2RADRB2ADRB1ADRB3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040084-A1 | COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT | NOVEN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040086-A2 | COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE AGENTS | NOVEN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |