Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 10/20 | 0.70 |
| ▸ | EGFR | P00533 | 9/20 | 0.69 |
| ▸ | JAK3 | P52333 | 1/20 | 0.68 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.64 |
| ▸ | NUAK2 | Q9H093 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30221455 | 1.00 | ALK (0.70) | ALKEGFRJAK3NUAK1NUAK2 | |
| SCHEMBL24900764 | 0.92 | JAK3 (0.80) | ALKEGFRJAK3NUAK1NUAK2 | |
| SCHEMBL30221290 | 0.92 | JAK3 (0.80) | ALKEGFRJAK3NUAK1NUAK2 | |
| SCHEMBL24900436 | 0.90 | EGFR (0.84) | ALKEGFRJAK3 | |
| SCHEMBL30221268 | 0.90 | EGFR (0.84) | ALKEGFRJAK3 | |
| SCHEMBL16752958 | 0.83 | ALK (1.00) | ALKEGFR | |
| SCHEMBL24900578 | 0.83 | EGFR (0.53) | ALKEGFRJAK3NUAK1NUAK2 | |
| SCHEMBL30221628 | 0.83 | EGFR (0.53) | ALKEGFRJAK3NUAK1NUAK2 | |
| SCHEMBL30221317 | 0.82 | ALK (0.76) | ALKEGFR | |
| SCHEMBL29229096 | 0.82 | ALK (0.76) | ALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |