Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.84 |
| ▸ | ALK | Q9UM73 | 13/20 | 0.75 |
| ▸ | JAK3 | P52333 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30221268 | 1.00 | EGFR (0.84) | EGFRALKJAK3 | |
| SCHEMBL30221290 | 0.92 | JAK3 (0.80) | EGFRALKJAK3 | |
| SCHEMBL24900764 | 0.92 | JAK3 (0.80) | EGFRALKJAK3 | |
| SCHEMBL30221317 | 0.92 | ALK (0.76) | EGFRALK | |
| SCHEMBL29229096 | 0.92 | ALK (0.76) | EGFRALK | |
| SCHEMBL24900435 | 0.90 | ALK (0.70) | EGFRALKJAK3 | |
| SCHEMBL30221455 | 0.90 | ALK (0.70) | EGFRALKJAK3 | |
| SCHEMBL24900774 | 0.90 | ALK (0.77) | EGFRALKJAK3 | |
| SCHEMBL30221523 | 0.90 | ALK (0.77) | EGFRALKJAK3 | |
| SCHEMBL28589814 | 0.89 | EGFR (0.94) | EGFRALKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |