Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18403079 | 0.96 | KCNH2 (0.43) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL19505906 | 0.96 | KCNH2 (0.43) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL27272370 | 0.96 | KCNH2 (0.43) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL23381218 | 0.96 | KCNH2 (0.43) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL19865652 | 0.96 | KCNH2 (0.43) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL18811892 | 0.96 | KCNH2 (0.43) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL23920816 | 0.92 | KCNH2 (0.41) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL9224767 | 0.92 | KCNH2 (0.41) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL25922262 | 0.92 | KCNH2 (0.39) | KCNH2KCNA5LMNAALDH1A1KMT2A | |
| SCHEMBL25933515 | 0.92 | KCNH2 (0.39) | KCNH2KCNA5LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |