Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25921496 | 1.00 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL25933515 | 1.00 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL9224767 | 0.92 | KCNH2 (0.41) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL23920816 | 0.92 | KCNH2 (0.41) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL24901344 | 0.92 | KCNH2 (0.40) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL16919618 | 0.92 | KMT2A (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL23435385 | 0.88 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL23381218 | 0.88 | KCNH2 (0.43) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL18403079 | 0.88 | KCNH2 (0.43) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL19865652 | 0.88 | KCNH2 (0.43) | KCNH2KCNA5LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142754-A1 | EZH1/2 INHIBITOR, PREPARATION THEREOF, AND USE THEREOF IN ANTI-TUMOR THERAPY | 江苏天士力帝益药业有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-1326519-C | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2007-07-18 | — | — | CN | disclosed |
| CN-1602191-A | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2005-03-30 | — | — | CN | disclosed |