Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246292 | 0.80 | SLC6A4 (0.47) | SLC6A4AAK1KDM4EPOLBPKM | |
| SCHEMBL29517897 | 0.80 | SLC6A4 (0.47) | SLC6A4AAK1KDM4EPOLBPKM | |
| SCHEMBL1330449 | 0.74 | SLC6A4 (0.49) | SLC6A4AAK1POLBDGAT1SMN1; SMN2 | |
| SCHEMBL2094492 | 0.74 | KDM4E (0.47) | SLC6A4AAK1USP28KDM4EPOLB | |
| SCHEMBL8157087 | 0.74 | SLC6A4 (0.43) | SLC6A4AAK1DGAT1PPARGPPARA | |
| SCHEMBL10337712 | 0.72 | SLC6A4 (0.42) | SLC6A4KDM4EPOLBPKMDGAT1 | |
| SCHEMBL21057235 | 0.72 | PPARG (0.44) | SLC6A4AAK1KDM4EPOLBPKM | |
| SCHEMBL21057233 | 0.72 | PPARG (0.44) | SLC6A4AAK1KDM4EPOLBPKM | |
| SCHEMBL6656426 | 0.72 | SLC6A4 (0.45) | SLC6A4AAK1KDM4EPOLBPKM | |
| SCHEMBL24901513 | 0.72 | SLC6A4 (0.42) | SLC6A4AAK1DGAT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |