Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817990 | 0.76 | PPARA (0.49) | SLC6A4AAK1FPR2SMN1; SMN2 | |
| SCHEMBL21057134 | 0.76 | PPARA (0.49) | SLC6A4AAK1FPR2SMN1; SMN2 | |
| SCHEMBL1330449 | 0.74 | SLC6A4 (0.49) | SLC6A4AAK1L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL6662309 | 0.73 | LDHA (0.44) | SLC6A4SMN1; SMN2HTTHPGDLMNA | |
| SCHEMBL6690262 | 0.73 | LDHA (0.44) | SLC6A4SMN1; SMN2HTTHPGDLMNA | |
| SCHEMBL6661078 | 0.73 | LDHA (0.44) | SLC6A4SMN1; SMN2HTTHPGDLMNA | |
| SCHEMBL24901503 | 0.72 | SLC6A4 (0.48) | SLC6A4AAK1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL29517897 | 0.72 | SLC6A4 (0.47) | SLC6A4AAK1L3MBTL1TSHRKDM4E | |
| SCHEMBL246292 | 0.72 | SLC6A4 (0.47) | SLC6A4AAK1L3MBTL1TSHRKDM4E | |
| SCHEMBL23368110 | 0.72 | HTT (0.43) | AAK1SMN1; SMN2HTTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |