SCHEMBL2094492

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3189588	0.85	KDM4E (0.45)	KDM4EPOLBPKMAAK1L3MBTL1
	SCHEMBL15300823	0.83	KDM4E (0.44)	KDM4EPOLBPKMAAK1L3MBTL1
	SCHEMBL15677337	0.82	KDM4E (0.42)	KDM4EPOLBPKMAAK1L3MBTL1
	SCHEMBL2094490	0.80	KDM4E (0.44)	KDM4EPOLBPKMAAK1L3MBTL1
	SCHEMBL1509935	0.80	HPGD (0.51)	AAK1L3MBTL1GAARAB9ASLC6A4
	SCHEMBL12144437	0.79	AAK1 (0.55)	KDM4EPOLBPKMAAK1L3MBTL1
	SCHEMBL1824099	0.78	NSD2 (0.46)	KDM4EPOLBPKMAAK1L3MBTL1
	SCHEMBL7769950	0.78	NSD2 (0.46)	KDM4EPOLBPKMAAK1L3MBTL1
	SCHEMBL3203774	0.78	PTGDR2 (0.64)	KDM4EPOLBPKML3MBTL1PTGDR2
	SCHEMBL14774842	0.78	USP28 (0.50)	KDM4EPOLBPKML3MBTL1USP28

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.