Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749860 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL28041056 | 0.84 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA4PAOXTSHR | |
| SCHEMBL3099807 | 0.83 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA4PAOXHIF1A | |
| SCHEMBL18207983 | 0.82 | PAOX (0.49) | CHRNB2CHRNB4CHRNA4PAOXTDP1 | |
| SCHEMBL9601255 | 0.79 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA4PAOXTSHR | |
| SCHEMBL3091042 | 0.79 | EPHX1 (0.52) | CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL2193077 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA4TDP1HIF1A | |
| Urea SCHEMBL28834377 | 0.78 | EPHX1 (0.47) | CHRNB2CHRNB4CHRNA4TSHRALOX15 | |
| SCHEMBL18207984 | 0.78 | PAOX (0.45) | PAOXGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL18632063 | 0.77 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA4TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | EVONIK OPERATIONS GMBH (DE) | 2026-02-03 | — | — | US | claimed |
| WO-2024175628-A1 | INHIBITING SOLIDS FORMATION IN CO2 POLYURETHANE PRODUCTION | EVONIK OPERATIONS GMBH (DE) | 2024-08-29 | — | — | WO | claimed |
| EP-4257625-A1 | HCFO-CONTAINING ISOCYANATE-REACTIVE COMPOSITIONS, RELATED FOAM-FORMING COMPOSITIONS AND FOAMS | Covestro LLC (US) | 2023-10-11 | — | — | EP | claimed |
| US-20230303757-A1 | HCFO-CONTAINING ISOCYANATE-REACTIVE COMPOSITIONS, RELATED FOAM-FORMING COMPOSITIONS AND FOAMS | COVESTRO LLC | 2023-09-28 | — | — | US | claimed |
| US-11559777-B2 | Microencapsulated polyaddition catalyst | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2023-01-24 | — | — | US | claimed |
| EP-3954722-A1 | PROCESS AND COMPOSITION FOR THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAM | Evonik Operations GmbH (DE) | 2022-02-16 | — | — | EP | claimed |
| US-20220033603-A1 | PROCESS AND COMPOSITION FOR THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2022-02-03 | — | — | US | claimed |
| EP-3592792-B1 | MICROENCAPSULATED POLYADDITION CATALYST | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2020-12-16 | — | — | EP | claimed |
| US-20200038830-A1 | Microencapsulated Polyaddition Catalyst | SIKA TECHNOLOGY AG (CH) | 2020-02-06 | — | — | US | claimed |
| US-10196476-B2 | Amine catalyst for improving the stability of polyurethane systems having halogen containing blowing agents | EVONIK DEGUSSA GMBH (DE) | 2019-02-05 | — | — | US | claimed |
| EP-1867669-A1 | Catalyst compositions for improving polyurethane foam performance | Air Products and Chemicals, Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| US-20070287761-A1 | Catalyst compositions for improving polyurethane foam performance | EVONIK OPERATIONS GMBH (DE) | 2007-12-13 | — | — | US | claimed |
| EP-1840144-A1 | Crosslinkers for minimizing deterioration of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2007-10-03 | — | — | EP | claimed |
| US-20070225393-A1 | Crosslinkers for minimizing deterioration of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. | 2007-09-27 | — | — | US | claimed |
| EP-1443065-B1 | Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams | AIR PROD & CHEM (US) | 2006-09-13 | — | — | EP | claimed |
| US-6825238-B2 | BISMUTH CARBOXYLATE OR BISMUTH SULFONATE HAVING LESS THAN 34% FREE ACID AS THE ORGANOMETALLIC CATALYST | AIR PRODUCTS AND CHEMICALS, INC. | 2004-11-30 | — | — | US | claimed |
| CN-1519264-A | Low acid organic metallic catalyst for producing soft, semisoft and hard urethane foam | �����Ʒ�뻯ѧ��˾ | 2004-08-11 | — | — | CN | claimed |
| EP-1443065-A1 | Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-08-04 | — | — | EP | claimed |
| US-20040147626-A1 | LOW ACID ORGANOMETALLIC CATALYST FOR THE PRODUCTION OF FLEXIBLE, SEMI-FLEXIBLE AND RIGID POLYURETHANE FOAMS | EVONIK DEGUSSA GMBH (DE) | 2004-07-29 | — | — | US | claimed |
| US-6114403-A | CONTROLLING THE LATITUDE OF THE FOAM USING A CATALYST MIXTURE CONSISTING OF 3-DIMETHYLAMINOPROPYL UREA AND N,N'-BIS(3-DIMETHYL-AMINOPROPYL) UREA | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-09-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | INTS9, PUF60, INTS6 | CHRNB2 3528/4885CHRNB4 2263/4885CHRNA4 2587/4885 |
| US-20220033603-A1 | PROCESS AND COMPOSITION FOR THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAM | PUF60, FUS, PCBP1 | CHRNB2 4532/4885CHRNB4 4301/4885CHRNA4 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.