Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447307 | 0.85 | — | — | |
| SCHEMBL3099807 | 0.85 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA4KDM4EMAPK1 | |
| SCHEMBL14557556 | 0.84 | PTGS1 (0.40) | CHRNB2CHRNB4CHRNA4PTGS1KCNH2 | |
| SCHEMBL3091042 | 0.81 | EPHX1 (0.52) | CHRNB2CHRNB4CHRNA4ACHEDNM1 | |
| SCHEMBL9601255 | 0.81 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA4KDM4EMAPK1 | |
| SCHEMBL10850963 | 0.79 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA4KDM4EMAPK1 | |
| SCHEMBL2490154 | 0.79 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA4TDP1CA2 | |
| SCHEMBL5385279 | 0.79 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA4KDM4EMAPK1 | |
| SCHEMBL18632063 | 0.79 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA4KDM4EMAPK1 | |
| SCHEMBL18665310 | 0.79 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA4KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| US-9150673-B2 | Process for preparing (meth)acrylic esters | BASF SE (DE) | 2015-10-06 | — | — | US | disclosed |
| CN-102037050-B | Heat-curing epoxy resin composition comprising an accelerator having a heteroatom | SIKA TECHNOLOGY AG | 2014-01-22 | — | — | CN | disclosed |
| US-20130178592-A1 | PROCESS FOR PREPARING (METH)ACRYLIC ESTERS | BASF SE (DE) | 2013-07-11 | — | — | US | disclosed |
| US-8263371-B2 | Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides | BASF AKTIENGESELLSCHAFT (DE) | 2012-09-11 | — | — | US | disclosed |
| US-7993886-B2 | Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides | BASF AKTIENGESELLSHAFT (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20110171697-A1 | CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES | BASF AKTIENGESELLSHAFT (DE) | 2011-07-14 | — | — | US | disclosed |
| CN-102037050-A | Heat-curing epoxy resin composition comprising an accelerator having a heteroatom | SIKA TECHNOLOGY AG | 2011-04-27 | — | — | CN | disclosed |
| US-20110067813-A1 | HEAT-CURING EPOXY RESIN COMPOSITION COMPRISING AN ACCELERATOR HAVING HETEROATOMS | SIKA TECHNOLOGY AG (CH) | 2011-03-24 | — | — | US | disclosed |
| US-20110067813-A1 | HEAT-CURING EPOXY RESIN COMPOSITION COMPRISING AN ACCELERATOR HAVING HETEROATOMS | SIKA TECHNOLOGY AG (CH) | 2011-03-24 | — | — | US | disclosed |
| US-20100285542-A1 | CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES | BASF AKTIENGESELLSHAFT (DE) | 2010-11-11 | — | — | US | disclosed |
| US-7816485-B2 | Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-19 | — | — | US | disclosed |
| WO-2009150059-A1 | HEAT-CURING EPOXY RESIN COMPOSITION COMPRISING AN ACCELERATOR HAVING HETEROATOMS | SIKA TECHNOLOGY AG (CH) | 2009-12-17 | — | — | WO | disclosed |
| EP-2128182-A1 | Heat hardened epoxy resin compound containing a catalyst with heteroatoms | Sika Technology AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| US-20060036063-A1 | Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-16 | — | — | US | disclosed |
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100285542-A1 | CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES | NAAA, APEH, NAA15 | CHRNB2 3258/4885CHRNB4 3211/4885CHRNA4 2427/4885 |
| US-20110171697-A1 | CATALYZED PREPARATION OF (METH)ACRYLATES OF N-HYDROXYALKYLATED AMIDES | NAAA, APEH, NAA15 | CHRNB2 3258/4885CHRNB4 3211/4885CHRNA4 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.