Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901470 | 0.81 | USP28 (0.38) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2414604 | 0.80 | SLC1A5 (0.43) | RECQLKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL6601275 | 0.80 | KMT2A (0.40) | RECQLKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL29855159 | 0.80 | SLC1A5 (0.43) | RECQLKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL23272217 | 0.80 | KMT2A (0.44) | RECQLKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL24901452 | 0.80 | ALDH1A1 (0.43) | KMT2ATSHRMEN1SMN1; SMN2LMNA | |
| SCHEMBL24901454 | 0.79 | KDM4E (0.40) | RECQLKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL31085195 | 0.78 | USP28 (0.38) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25875508 | 0.75 | TSHR (0.39) | RECQLKMT2ATSHRMEN1SMN1; SMN2 | |
| SCHEMBL13020197 | 0.74 | TSHR (0.44) | RECQLKMT2ATSHRMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |