Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447729 | 0.83 | ADORA2A (0.60) | ADORA2A | |
| SCHEMBL19596873 | 0.80 | ADORA2A (0.68) | ADORA2A | |
| SCHEMBL5653322 | 0.79 | ADORA2A (0.71) | ADORA2AADORA1 | |
| SCHEMBL6047383 | 0.79 | KDM4E (0.56) | ADORA2AADORA3ADORA1 | |
| SCHEMBL6047213 | 0.78 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL12612295 | 0.77 | ADORA2A (0.68) | ADORA2AADORA1 | |
| SCHEMBL3541623 | 0.77 | ADORA2A (0.68) | ADORA2AADORA3ADORA1 | |
| SCHEMBL9329196 | 0.77 | ADORA2A (1.00) | ADORA2AADORA3ADORA1 | |
| SCHEMBL6623709 | 0.76 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL27340603 | 0.75 | ADORA2A (0.48) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027075-A1 | SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027075-A1 | SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS | ADORA2A, ADORA2B, ENTPD5 | ADORA2A 1/4885ADORA3 5/4885ADORA1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.