Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 9/20 | 0.36 |
| ▸ | JAK3 | P52333 | 4/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | TYK2 | P29597 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24902207 | 0.86 | PGR (0.37) | TPH1JAK2JAK3JAK1TYK2 | |
| SCHEMBL26717251 | 0.86 | KDM5A (0.37) | KDM5AJAK2JAK3JAK1TYK2 | |
| SCHEMBL24902070 | 0.81 | JAK2 (0.49) | JAK2JAK3JAK1TYK2PTGS2 | |
| SCHEMBL30864342 | 0.81 | JAK2 (0.49) | JAK2JAK3JAK1TYK2PTGS2 | |
| SCHEMBL24902082 | 0.81 | JAK2 (0.49) | JAK2JAK3JAK1TYK2PTGS2 | |
| SCHEMBL30223620 | 0.80 | JAK1 (0.52) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL24902014 | 0.80 | JAK1 (0.52) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL24902114 | 0.80 | JAK1 (0.52) | JAK2JAK3JAK1TYK2STAT3 | |
| SCHEMBL24902066 | 0.80 | PTGS1 (0.40) | TPH1PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL26610797 | 0.76 | JAK2 (0.49) | JAK2JAK3JAK1TYK2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001045-A9 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海椿安生物医药科技有限公司 | 2023-10-26 | — | — | WO | disclosed |
| WO-2023001045-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海椿安生物医药科技有限公司 | 2023-01-26 | — | — | WO | disclosed |