Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616094 | 0.82 | TP53 (0.36) | ALDH1A1TSHRCYP1A2CYP2D6HPGD | |
| SCHEMBL2912079 | 0.82 | TP53 (0.36) | ALDH1A1TSHRCYP1A2CYP2D6HPGD | |
| SCHEMBL7033231 | 0.76 | ANPEP (0.37) | ALDH1A1TAAR1GRM2 | |
| SCHEMBL4449690 | 0.75 | TP53 (0.32) | ALDH1A1CYP1A2CYP2C19HSD17B10MAPK1 | |
| Carbon Monoxide SCHEMBL11677050 | 0.73 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL7557905 | 0.73 | ACHE (0.43) | ALDH1A1TSHRTAAR1CYP1A2 | |
| SCHEMBL18204216 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TAAR1PLCG1IDO1MAPK1 | |
| SCHEMBL4438970 | 0.71 | CYP3A4 (0.41) | ALDH1A1TSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2967314 | 0.71 | — | — | |
| SCHEMBL7194415 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRTAAR1RECQLCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762380-B1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-2041150-B1 | DIPHOSPHINE LIGANDS | SOLVIAS AG (CH) | 2011-10-26 | — | — | EP | disclosed |
| US-20100029967-A1 | Diphosphine ligands | SOLVIAS AG (CH) | 2010-02-04 | — | — | US | disclosed |
| CN-101479284-A | Diphosphine ligands | SOLVIAS AG (CH) | 2009-07-08 | — | — | CN | disclosed |
| EP-2041150-A1 | DIPHOSPHINE LIGANDS | Solvias AG (CH) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008000815-A1 | DIPHOSPHINE LIGANDS | SOLVIAS AG (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029967-A1 | Diphosphine ligands | C1S, CHRM1, CCNE1 | ALDH1A1 4523/4885TSHR 1269/4885TAAR1 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.