Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408206 | 0.89 | — | — | |
| SCHEMBL129496 | 0.88 | CHRM2 (0.40) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL5062392 | 0.87 | CHRM2 (0.40) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL3414469 | 0.87 | CHRM2 (0.39) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| Water SCHEMBL29151581 | 0.87 | — | — | |
| SCHEMBL4239133 | 0.86 | KMT2A (0.43) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL126114 | 0.84 | CHRM2 (0.42) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL3911963 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| Phosphoric Acid SCHEMBL29160732 | 0.80 | — | — | |
| SCHEMBL22345800 | 0.79 | CHRM2 (0.46) | CHRM2CHRM1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380983-A2 | RAGE fusion proteins, formulations, and methods of use thereof | TransTech Pharma Inc. (US) | 2011-10-26 | — | — | EP | disclosed |