Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062392 | 0.87 | CHRM2 (0.40) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL2490415 | 0.86 | CHRM2 (0.40) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL3911963 | 0.84 | CHRM2 (0.39) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL126114 | 0.84 | CHRM2 (0.42) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL129496 | 0.81 | CHRM2 (0.40) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL3414469 | 0.80 | CHRM2 (0.39) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL1919485 | 0.79 | KMT2A (0.47) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL22345800 | 0.79 | CHRM2 (0.46) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL4259360 | 0.78 | HTT (0.50) | KMT2ALMNAHTTCHRM2CHRM1 | |
| SCHEMBL64211 | 0.76 | CHRM2 (0.47) | KMT2ALMNAHTTCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139939-A2 | HYBRID NANOPARTICLES AS ANTI-CANCER THERAPEUTIC AGENTS AND DUAL THERAPEUTIC/IMAGING CONTRAST AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-11-19 | — | — | WO | disclosed |
| US-6656711-B2 | Concentrating epothilones in culture from Sorangium strains obtained by mutagenesis; antitumor agents | NOVARTIS AG (CH) | 2003-12-02 | — | — | US | disclosed |