Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062392 | 0.86 | CHRM2 (0.40) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL4239133 | 0.84 | KMT2A (0.43) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL2490415 | 0.84 | CHRM2 (0.40) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL126114 | 0.83 | CHRM2 (0.42) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL5062396 | 0.81 | CHRM2 (0.40) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL129496 | 0.80 | CHRM2 (0.40) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL3089652 | 0.79 | CHRM2 (0.39) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL4606042 | 0.79 | CHRM2 (0.45) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL3414469 | 0.79 | CHRM2 (0.39) | CHRM2CHRM1ALDH1A1KDM4EKMT2A | |
| SCHEMBL7084580 | 0.78 | CHRM2 (0.41) | CHRM2CHRM1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189937-B1 | PURIFIED ANTIGEN FOR ALZHEIMER'S DISEASE, AND METHODS OF OBTAINING AND USING SAME | MOLECULAR GERIATRICS CORP (US) | 2009-03-18 | — | — | EP | disclosed |
| US-20080181883-A1 | Purified Antigen for Alzheimer's Disease and Methods of Obtaining and Using Same | APPLIED NEUROSOLUTIONS FORMALLY KNOWN AS MOLECULAR GERIATRICS CORPORATION | 2008-07-31 | — | — | US | disclosed |
| US-20050272094-A1 | Purified antigen for Alzheimer's disease and methods of obtaining and using same | MOLECULAR GERIATRICS CORPORATION | 2005-12-08 | — | — | US | disclosed |
| US-6864062-B2 | Purified antigen for Alzheimer's disease and methods of obtaining and using same | MOLECULAR GERIATRICS CORPORATION (US) | 2005-03-08 | — | — | US | disclosed |
| US-20030113896-A1 | Purified antigen for Alzheimer's disease and methods of obtaining and using same | ZINKOWSKI RAYMOND P (US) | 2003-06-19 | — | — | US | disclosed |
| EP-1189937-A1 | PURIFIED ANTIGEN FOR ALZHEIMER'S DISEASE, AND METHODS OF OBTAINING AND USING SAME | MOLECULAR GERIATRICS CORPORATION (US) | 2002-03-27 | — | — | EP | disclosed |
| US-20020002270-A1 | PURIFIED ANTIGEN FOR ALZHEIMER'S DISEASE, AND METHODS OF OBTAINING AND USING SAME | MOLECULAR GERIATRICS CORPORATION | 2002-01-03 | — | — | US | disclosed |
| WO-2000078807-A1 | PURIFIED ANTIGEN FOR ALZHEIMER'S DISEASE, AND METHODS OF OBTAINING AND USING SAME | MOLECULAR GERIATRICS CORPORATION (US) | 2000-12-28 | — | — | WO | disclosed |