SCHEMBL24905567

SCHEMBL24905567

CC1(C)c2ccccc2-c2c(-c3c4ccccc4c(-c4ccc(-c5cccc6ccccc56)cc4)c4ccccc34)cccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 2/20 0.40
ENPP3 O14638 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
PPARG P37231 8/20 0.37
PPARA Q07869 8/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
PPARD Q03181 1/20 0.37
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24648485 0.94 DHFR (0.38) ENPP1ENPP3CA12CA1CA2
SCHEMBL13487167 0.87 MCL1 (0.33) ENPP1ENPP3CA12CA1CA2
SCHEMBL13487174 0.86 MAPK11 (0.38) ENPP1ENPP3CHRNB4CHRNA3KDM4E
SCHEMBL13487190 0.85 CYP1A2 (0.38) ENPP1PPARGPPARACYP2C9CYP2C19
SCHEMBL13487233 0.84 MCL1 (0.34) ENPP1ENPP3PPARGPPARACYP2C9
SCHEMBL13487189 0.84 SCN5A (0.35) ENPP1HDAC8HDAC6PPARGPPARA
SCHEMBL13487188 0.84 MCL1 (0.37) CA1CA2CYP2C9CYP2C19MCL1
SCHEMBL18463592 0.83 ENPP3 (0.41) ENPP1ENPP3CA12CA1CA2
SCHEMBL26884797 0.83 HDAC8 (0.40) ENPP1ENPP3CA12CA1CA2
SCHEMBL26001736 0.83 ENPP1 (0.38) ENPP1ENPP3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed