Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL961342 | 0.80 | SLC6A3 (0.31) | SLC6A3 | |
| SCHEMBL961349 | 0.76 | PSEN1 (0.33) | — | |
| SCHEMBL961340 | 0.70 | PSEN1 (0.38) | — | |
| SCHEMBL960585 | 0.69 | PSEN1 (0.42) | — | |
| SCHEMBL963213 | 0.69 | AAK1 (0.37) | — | |
| SCHEMBL963212 | 0.69 | F11 (0.36) | — | |
| SCHEMBL960939 | 0.66 | AR (0.33) | — | |
| SCHEMBL962540 | 0.61 | POLB (0.41) | SLC6A3 | |
| SCHEMBL961183 | 0.58 | POLB (0.41) | SLC6A3 | |
| SCHEMBL827946 | 0.57 | SMARCA2 (0.38) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379553-A1 | BICYCLIC COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | Bristol-Myers Squibb Company (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010083141-A1 | BICYCLIC COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-07-22 | — | — | WO | disclosed |