SCHEMBL2490831

SCHEMBL2490831

CCOc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.75
CYP2C19 P33261 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
KDM4E B2RXH2 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
ALDH1A1 P00352 3/20 0.52
MAPT P10636 5/20 0.52
EDNRA P25101 1/20 0.52
HTR6 P50406 2/20 0.51
CYP3A4 P08684 1/20 0.51
AURKA O14965 1/20 0.49
DHFR P00374 1/20 0.49
TSHR P16473 1/20 0.49
POLB P06746 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
AKT1 P31749 1/20 0.47
ADRA1A P35348 1/20 0.47
PDE4A P27815 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29471766 1.00 LMNA (0.75) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL29377020 0.86 LMNA (1.00) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL10777132 0.86 LMNA (1.00) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL93617 0.86 LMNA (1.00) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL29360723 0.86 LMNA (1.00) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL27484423 0.85 LMNA (0.97) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL11516439 0.85 LMNA (0.97) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL11026411 0.83 LMNA (0.94) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL28086651 0.80 LMNA (0.77) LMNACYP2C19SMN1; SMN2KDM4ENPSR1
Sulfamethoxypyridazine SCHEMBL28567679 0.76 LMNA (0.65) LMNACYP2C19SMN1; SMN2KDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
EP-2380208-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. du Pont de Nemours and Company (US) 2011-10-26 EP disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed