SCHEMBL24908677

SCHEMBL24908677

CCOCCNC(=O)C(C(C)C)N1C(=O)c2cc(Oc3ccc(C)cc3)c3c4c(Oc5ccc(C)cc5)cc5c6c(cc(Oc7ccc(C)cc7)c(c7c(Oc8ccc(C)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)NCCOCC)C(C)C)C5=O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
TP53 P04637 2/20 0.36
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
PCNA P12004 1/20 0.33
POLB P06746 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.32
USP2 O75604 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24740737 0.86 CTSK (0.33) SMN1; SMN2TP53PSEN1PSEN2APH1B
SCHEMBL24908678 0.82 SMN1; SMN2 (0.44) SMN1; SMN2TP53TSHR
SCHEMBL24704756 0.80 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1HPGDTP53
SCHEMBL24705310 0.80 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1KDM4EHPGDTP53
SCHEMBL24705323 0.80 LMNA (0.34) SMN1; SMN2ALDH1A1TP53TSHR
SCHEMBL24704928 0.79 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL24739613 0.79 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1TP53
SCHEMBL24908716 0.79 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1KDM4EPSEN1PSEN2
SCHEMBL24704965 0.78 SMN1; SMN2 (0.33) SMN1; SMN2TP53
SCHEMBL24705125 0.78 SMN1; SMN2 (0.41) SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed