SCHEMBL24908682

SCHEMBL24908682

CC(C)C(C(=O)NC(C(F)(F)F)C(F)(F)F)N1C(=O)c2cc(Oc3ccc(C(C)(C)C)cc3)c3c4c(Oc5ccc(C(C)(C)C)cc5)cc5c6c(cc(Oc7ccc(C(C)(C)C)cc7)c(c7c(Oc8ccc(C(C)(C)C)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)NC(C(F)(F)F)C(F)(F)F)C(C)C)C5=O

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
HPGD P15428 1/20 0.32
TNF P01375 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
PLAU P00749 1/20 0.31
ELANE P08246 1/20 0.31
DNMT1 P26358 3/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909333 0.86 DNMT1 (0.31) ALDH1A1NPSR1HPGDDNMT1
SCHEMBL24908667 0.85 TP53 (0.48) TP53TSHRALDH1A1NPSR1HPGD
SCHEMBL24908715 0.84 DNMT1 (0.39) TP53ALDH1A1NPSR1HPGDTNF
SCHEMBL24909038 0.82 MAPT (0.34) ALDH1A1NPSR1HPGDTNFSMN1; SMN2
SCHEMBL24908948 0.82 TNF (0.31) TNF
SCHEMBL24909227 0.81 TP53 (0.44) TP53TSHRALDH1A1NPSR1HPGD
SCHEMBL24909623 0.79 SMN1; SMN2 (0.44) ALDH1A1NPSR1SMN1; SMN2KMT2AMAPT
SCHEMBL24909308 0.79 L3MBTL1 (0.39) TP53ALDH1A1NPSR1DNMT1KMT2A
SCHEMBL24909622 0.79 DNMT1 (0.33) TSHRALDH1A1NPSR1HPGDTNF
SCHEMBL24909095 0.78 POLB (0.40) ALDH1A1SMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed