Sugi Predict

Sugi Predict / Compounds / SCHEMBL24909095

SCHEMBL24909095

SCHEMBL24909095

CC(C(=O)NC(C(F)(F)F)C(F)(F)F)N1C(=O)c2cc(Oc3ccc(-c4ccccc4)cc3)c3c4c(Oc5ccc(-c6ccccc6)cc5)cc5c6c(cc(Oc7ccc(-c8ccccc8)cc7)c(c7c(Oc8ccc(-c9ccccc9)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(C)C(=O)NC(C(F)(F)F)C(F)(F)F)C5=O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ MAPT P10636 2/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ ALDH1A1 P00352 3/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ACACB O00763 3/20 0.35
▸ ACACA Q13085 3/20 0.35
▸ HTT P42858 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ ALOX15 P16050 1/20 0.34
▸ MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909121 0.83 PTPN1 (0.36) ALDH1A1
SCHEMBL24908740 0.81 ALDH1A1 (0.39) MAPTALDH1A1LMNA
SCHEMBL24908682 0.78 TP53 (0.34) MAPTSMN1; SMN2ALDH1A1LMNA
SCHEMBL24705144 0.78 SMN1; SMN2 (0.39) POLBL3MBTL1MAPTSMN1; SMN2ALDH1A1
SCHEMBL24908681 0.78 TP53 (0.42) MAPTSMN1; SMN2ALDH1A1KDM4EACACB
SCHEMBL24908696 0.78 NPSR1 (0.35) POLBL3MBTL1LMNAMAPK1
SCHEMBL24909082 0.76 LMNA (0.32) SMN1; SMN2ALDH1A1LMNA
SCHEMBL24705465 0.76 MCL1 (0.48) POLBMAPTALDH1A1KDM4E
SCHEMBL24908950 0.74 LMNA (0.44) SMN1; SMN2LMNA
SCHEMBL24909610 0.72 KDM4E (0.43) POLBL3MBTL1SMN1; SMN2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 — — US disclosed