SCHEMBL24908753

SCHEMBL24908753

CC(C)C(C(=O)Nc1ccc(Cl)cc1)N1C(=O)c2cc(Oc3ccc(-c4ccccc4)cc3)c3c4c(Oc5ccc(-c6ccccc6)cc5)cc5c6c(cc(Oc7ccc(-c8ccccc8)cc7)c(c7c(Oc8ccc(-c9ccccc9)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)Nc1ccc(Cl)cc1)C(C)C)C5=O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.52
KMT2A Q03164 2/20 0.46
XIAP P98170 1/20 0.44
TSHR P16473 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.41
PNLIP P16233 2/20 0.41
LMNA P02545 1/20 0.41
FPR1 P21462 1/20 0.41
F11 P03951 1/20 0.39
KLKB1 P03952 1/20 0.39
MEN1 O00255 1/20 0.39
NPY5R Q15761 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24740745 0.89 TP53 (0.46) TP53KMT2AXIAPTSHRKDM4E
SCHEMBL24908681 0.83 TP53 (0.42) TP53KMT2ATSHRKDM4EGAA
SCHEMBL24739948 0.82 FPR1 (0.41) TP53KMT2AXIAPTSHRKDM4E
SCHEMBL24908667 0.82 TP53 (0.48) TP53KMT2AXIAPTSHRKDM4E
SCHEMBL24908950 0.81 LMNA (0.44) TP53GAASMN1; SMN2LMNA
SCHEMBL24705333 0.81 TP53 (0.49) TP53KMT2AXIAPTSHRKDM4E
SCHEMBL24909067 0.81 TP53 (0.41) TP53KMT2AGAAMAPTSMN1; SMN2
SCHEMBL24909229 0.79 TP53 (0.47) TP53KMT2AXIAPTSHRKDM4E
SCHEMBL24909227 0.76 TP53 (0.44) TP53KMT2ATSHRKDM4EGAA
SCHEMBL24705465 0.74 MCL1 (0.48) TP53KMT2AKDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed