SCHEMBL24908756

SCHEMBL24908756

CCCc1ccc(Oc2cc3c4c(cc(Oc5ccc(CCC)cc5)c5c6c(Oc7ccc(CCC)cc7)cc7c8c(cc(Oc9ccc(CCC)cc9)c(c2c45)c86)C(=O)N(C(C)C(=O)N2CCCCC2)C7=O)C(=O)N(C(C)C(=O)N2CCCCC2)C3=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
HTT P42858 4/20 0.50
KMT2A Q03164 6/20 0.41
MEN1 O00255 4/20 0.41
POLB P06746 2/20 0.41
NPC1 O15118 1/20 0.39
GAA P10253 2/20 0.39
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
LMNA P02545 4/20 0.36
NPSR1 Q6W5P4 3/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ACACB O00763 4/20 0.34
ACACA Q13085 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24739946 0.77 TSHR (0.45) ALDH1A1HTTKMT2AMEN1POLB
SCHEMBL24909204 0.76 NPC1 (0.46) ALDH1A1HTTKMT2APOLBNPC1
SCHEMBL24909033 0.76 TSHR (0.36) ALDH1A1HTTKMT2AMEN1POLB
SCHEMBL24909623 0.76 SMN1; SMN2 (0.44) ALDH1A1HTTKMT2AMEN1NPC1
SCHEMBL24740687 0.76 ALDH1A1 (0.32) ALDH1A1HTT
SCHEMBL24909392 0.75 POLB (0.40) ALDH1A1HTTKMT2AMEN1POLB
SCHEMBL24705308 0.74 TSHR (0.42) ALDH1A1HTTKMT2APOLBNPC1
SCHEMBL24908979 0.71 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1NPC1GAA
SCHEMBL24909610 0.70 KDM4E (0.43) ALDH1A1HTTKMT2APOLBGAA
SCHEMBL24739797 0.70 MCL1 (0.42) ALDH1A1KMT2APOLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed