SCHEMBL24705308

SCHEMBL24705308

CO[SiH2]CN1CCN(C(=O)C(C)N2C(=O)c3cc(Oc4ccc(C)cc4)c4c5c(Oc6ccc(C)cc6)cc6c7c(cc(Oc8ccc(C)cc8)c(c8c(Oc9ccc(C)cc9)cc(c3c48)C2=O)c75)C(=O)N(C(C)C(=O)N2CCN(C[SiH2]OC)CC2)C6=O)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.40
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.36
MTNR1B P49286 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.32
LPAR1 Q92633 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
FAAH O00519 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909204 0.86 NPC1 (0.46) TSHRNPC1ALDH1A1HTTGAA
SCHEMBL24704995 0.82 NPC1 (0.38) TSHRNPC1ALDH1A1HTTGAA
SCHEMBL24909610 0.76 KDM4E (0.43) TSHRALDH1A1HTTGAAKMT2A
SCHEMBL24908694 0.74 NPC1 (0.42) TSHRNPC1KMT2ALMNASMN1; SMN2
SCHEMBL24908756 0.74 ALDH1A1 (0.50) TSHRNPC1ALDH1A1HTTGAA
SCHEMBL24704939 0.72 ALDH1A1 (0.37) NPC1ALDH1A1KMT2ALMNASMN1; SMN2
SCHEMBL24705626 0.70 MCL1 (0.45) ALDH1A1GAAKMT2ALPAR1LPAR3
SCHEMBL24705099 0.67 ALDH1A1 (0.60) TSHRALDH1A1HTTGAAKMT2A
SCHEMBL24909279 0.67 KMT2A (0.40) TSHRALDH1A1GAAKMT2AKDM4E
SCHEMBL24909290 0.66 LPAR3 (0.68) ALDH1A1HTTKMT2AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389014-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM MANUFACTURED THEREFROM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389014-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM MANUFACTURED THEREFROM, BACKLIGHT UNIT, AND DISPLAY DEVICE NOTUM, THEM6, FAR1 TSHR 4390/4885NPC1 2505/4885ALDH1A1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.