SCHEMBL24909006

SCHEMBL24909006

CCOCCNC(=O)C(CC(F)(F)F)N1C(=O)c2cc(Oc3ccc(C(C)C)cc3)c3c4c(Oc5ccc(C(C)C)cc5)cc5c6c(cc(Oc7ccc(C(C)C)cc7)c(c7c(Oc8ccc(C(C)C)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(CC(F)(F)F)C(=O)NCCOCC)C5=O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.34
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
PCNA P12004 1/20 0.33
GAA P10253 1/20 0.31
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908716 0.80 SMN1; SMN2 (0.39) SMN1; SMN2PSEN1PSEN2APH1BNCSTN
SCHEMBL24909005 0.79 DNMT1 (0.35) SMN1; SMN2TP53
SCHEMBL24908737 0.79 ALDH1A1 (0.35) SMN1; SMN2LMNATP53
SCHEMBL24704951 0.78 POLB (0.30)
SCHEMBL24908684 0.78 MAPT (0.44) GAALMNA
SCHEMBL24705654 0.78 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL24908677 0.77 SMN1; SMN2 (0.43) SMN1; SMN2PSEN1PSEN2APH1BNCSTN
SCHEMBL24705129 0.77 ALDH1A1 (0.33) SMN1; SMN2GAATP53
SCHEMBL24739784 0.76 POLB (0.33) GAA
SCHEMBL24705653 0.76 SMN1; SMN2 (0.36) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed