SCHEMBL24909034

SCHEMBL24909034

CN(C)C(=O)C(c1cccnc1)N1C(=O)c2cc(Oc3ccccc3)c3c4c(Oc5ccccc5)cc5c6c(cc(Oc7ccccc7)c(c7c(Oc8ccccc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)N(C)C)c1cccnc1)C5=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 5/20 0.38
MAPK1 P28482 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 1/20 0.35
ALOX15 P16050 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
KCNH2 Q12809 1/20 0.34
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CREBBP Q92793 1/20 0.33
SLC1A2 P43004 1/20 0.33
PDE4D Q08499 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909135 0.81 NPY2R (0.40) KCNA5HSD17B10CYP11B1CYP11B2TSHR
SCHEMBL24909093 0.77 ABHD6 (0.38) KCNA5CYP11B1CYP11B2
SCHEMBL24909304 0.76 CYP3A4 (0.37) MAPK1ALDH1A1HSD17B10ALOX15TSHR
SCHEMBL24909279 0.73 KMT2A (0.40) MAPK1ALDH1A1HSD17B10ALOX15TSHR
SCHEMBL24909325 0.73 SMN1; SMN2 (0.35) ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL24909036 0.73 ALOX15 (0.46) MAPK1ALDH1A1HSD17B10ALOX15SMN1; SMN2
SCHEMBL24909235 0.72 KMT2A (0.37) ALDH1A1PDE4D
SCHEMBL24909122 0.72 KMT2A (0.37) ALDH1A1PDE4D
SCHEMBL24908945 0.72 TNF (0.39) MAPK1ALDH1A1HSD17B10
SCHEMBL24705091 0.71 LPAR1 (0.37) MAPK1ALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed