SCHEMBL24909052

SCHEMBL24909052

Cc1cc(C)cc(Oc2cc3c4c(cc(Oc5cc(C)cc(C)c5)c5c6c(Oc7cc(C)cc(C)c7)cc7c8c(cc(Oc9cc(C)cc(C)c9)c(c2c45)c86)C(=O)N(C(CC(F)(F)F)C(=O)NC2CCCCC2)C7=O)C(=O)N(C(CC(F)(F)F)C(=O)NC2CCCCC2)C3=O)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
KMT2A Q03164 4/20 0.38
TAS1R3 Q7RTX0 2/20 0.35
TAS1R1 Q7RTX1 2/20 0.35
TAS1R2 Q8TE23 2/20 0.35
EPHX2 P34913 1/20 0.33
MEN1 O00255 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909335 0.94 KMT2A (0.40) TP53KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL24908749 0.86 MEN1 (0.31) TP53KMT2AMEN1TDP1
SCHEMBL24909053 0.84 POLB (0.33) TP53KMT2AMEN1CYP3A4CYP2D6
SCHEMBL24908977 0.82 KMT2A (0.41) TP53KMT2AMEN1TSHRPOLB
SCHEMBL24704929 0.80 CNR1 (0.32) TP53KMT2A
SCHEMBL24908726 0.79 LMNA (0.45) KMT2AEPHX2MEN1LMNAHPGD
SCHEMBL24908738 0.78 GAA (0.36) TP53KMT2AMEN1CYP3A4CYP2C9
SCHEMBL24705653 0.78 SMN1; SMN2 (0.36)
SCHEMBL24909023 0.77 HPGD (0.44) KMT2AEPHX2LMNAHPGDTSHR
SCHEMBL24909013 0.76 SMN1; SMN2 (0.38) TP53KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed