SCHEMBL24909335

SCHEMBL24909335

Cc1cc(C)cc(Oc2cc3c4c(cc(Oc5cc(C)cc(C)c5)c5c6c(Oc7ccc(C)c(C)c7)cc7c8c(cc(Oc9cc(C)cc(C)c9)c(c2c45)c86)C(=O)N(C(CC(F)(F)F)C(=O)NC2CCCCC2)C7=O)C(=O)N(C(CC(F)(F)F)C(=O)NC2CCCCC2)C3=O)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 2/20 0.38
MAPT P10636 1/20 0.34
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
TAS1R2 Q8TE23 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909052 0.94 TP53 (0.39) KMT2AMEN1TP53MAPTTAS1R3
SCHEMBL24908749 0.80 MEN1 (0.31) KMT2AMEN1TP53
SCHEMBL24908977 0.80 KMT2A (0.41) KMT2AMEN1TP53
SCHEMBL24909053 0.78 POLB (0.33) KMT2AMEN1TP53HPGDL3MBTL1
SCHEMBL24704929 0.78 CNR1 (0.32) KMT2ATP53
SCHEMBL24908726 0.77 LMNA (0.45) KMT2AMEN1LMNAHPGDNPC1
SCHEMBL24909023 0.76 HPGD (0.44) KMT2ALMNAHPGDNPC1RAB9A
SCHEMBL24909096 0.76 SMN1; SMN2 (0.33) TAS1R3TAS1R1
SCHEMBL24705574 0.75 LIPG (0.33) MAPTRAB9A
SCHEMBL24908738 0.75 GAA (0.36) KMT2AMEN1TP53MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed