SCHEMBL24909073

SCHEMBL24909073

CCN1CCN(C(=O)C(Cc2cc3ccccc3[nH]2)N2C(=O)c3cc(Oc4cccc(OC)c4)c4c5c(Oc6cccc(OC)c6)cc6c7c(cc(Oc8cccc(OC)c8)c(c8c(Oc9cccc(OC)c9)cc(c3c48)C2=O)c75)C(=O)N(C(Cc2cc3ccccc3[nH]2)C(=O)N2CCN(CC)CC2)C6=O)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 7/20 0.42
DRD2 P14416 7/20 0.42
HRH4 Q9H3N8 1/20 0.40
KMT2A Q03164 4/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
RAD52 P43351 2/20 0.38
CRHBP P24387 2/20 0.37
CRHR2 Q13324 2/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
MEN1 O00255 2/20 0.37
ADRB1 P08588 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2C P18825 1/20 0.36
HTR2B P41595 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
UBE2N P61088 2/20 0.36
POLB P06746 1/20 0.36
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908757 0.82 TSHR (0.36) DRD3DRD2KMT2ARAB9AMEN1
SCHEMBL24908760 0.80 TSHR (0.39) DRD3DRD2KMT2ANPC1RAB9A
SCHEMBL24908734 0.74 TSHR (0.46) KMT2AMEN1POLB
SCHEMBL24909183 0.74 GAA (0.39) KMT2AMEN1POLB
SCHEMBL24909044 0.73 MAPT (0.35) KMT2AMEN1POLB
SCHEMBL24704843 0.73 FAAH (0.36) KMT2AMEN1SIGMAR1TP53
SCHEMBL24908761 0.72 TSHR (0.38) DRD3DRD2KMT2ARAD52MEN1
SCHEMBL24909324 0.71 ALDH1A1 (0.41) KMT2AMEN1POLBTP53
SCHEMBL24705818 0.70 ALDH1A1 (0.40) KMT2AMEN1POLBTP53
SCHEMBL24705830 0.69 KDM4E (0.40) KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed