SCHEMBL24909084

SCHEMBL24909084

COc1cc(OC)cc(OC(=O)C(C)N2C(=O)c3cc(Oc4ccc(-c5ccccc5)cc4C)c4c5c(Oc6ccc(-c7ccccc7)cc6C)cc6c7c(cc(Oc8ccc(-c9ccccc9)cc8C)c(c8c(Oc9ccc(-c%10ccccc%10)cc9C)cc(c3c48)C2=O)c75)C(=O)N(C(C)C(=O)Oc2cc(OC)cc(OC)c2)C6=O)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
USP2 O75604 1/20 0.36
TSHR P16473 1/20 0.35
POLB P06746 2/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
FFAR1 O14842 2/20 0.35
TNF P01375 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HSD17B10 Q99714 1/20 0.34
BACE1 P56817 1/20 0.33
ABCB1 P08183 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908955 0.82 TNF (0.35) MAPTSMN1; SMN2TNF
SCHEMBL24909191 0.77 TNF (0.33) MAPTSMN1; SMN2L3MBTL1TNF
SCHEMBL24908996 0.76 TP53 (0.41) MAPTLMNAL3MBTL1TDP1POLB
SCHEMBL24705837 0.72 LMNA (0.42) LMNAUSP2KDM4E
SCHEMBL24908750 0.70 TNF (0.32) MAPTSMN1; SMN2LMNAL3MBTL1TDP1
SCHEMBL24908945 0.70 TNF (0.39) MAPTLMNAL3MBTL1POLBTNF
SCHEMBL24908708 0.70 ALDH1A1 (0.45) MAPTSMN1; SMN2LMNAPOLBKDM4E
SCHEMBL24909187 0.70 SMN1; SMN2 (0.42) MAPTSMN1; SMN2LMNAL3MBTL1TSHR
SCHEMBL24705465 0.68 MCL1 (0.48) MAPTPOLBKDM4E
SCHEMBL24909610 0.66 KDM4E (0.43) SMN1; SMN2LMNAL3MBTL1USP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed