SCHEMBL24909196

SCHEMBL24909196

CC(C)(C)c1ccc(Oc2cc3c4c(cc(Oc5ccc(C(C)(C)C)cc5)c5c6c(Oc7ccc(C(C)(C)C)cc7)cc7c8c(cc(Oc9ccc(C(C)(C)C)cc9)c(c2c45)c86)C(=O)N(C(C(=O)NC2CCCCC2)c2ccncc2)C7=O)C(=O)N(C(C(=O)NC2CCCCC2)c2ccncc2)C3=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.41
NR1H4 Q96RI1 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 4/20 0.36
MDM2 Q00987 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
EPHX1 P07099 1/20 0.36
EPHX2 P34913 1/20 0.36
GAA P10253 1/20 0.35
KDR P35968 1/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
YAP1 P46937 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909575 0.88 MAPK1 (0.33) MAPK1NR1H4KMT2ATSHRMDM2
SCHEMBL24909039 0.85 EPHX2 (0.40) NR1H4KMT2ATSHRNPSR1ALDH1A1
SCHEMBL24909079 0.81 TSHR (0.46) MAPK1KMT2ATSHRNPSR1ALDH1A1
SCHEMBL24908687 0.74 LMNA (0.33) MAPK1NPSR1CYP3A4MAPT
SCHEMBL24909227 0.74 TP53 (0.44) MAPK1KMT2ATSHRPOLBNPSR1
SCHEMBL24908968 0.74 RAF1 (0.39) MAPK1POLBNPSR1ALDH1A1MAPT
SCHEMBL24908679 0.73 MAPT (0.34) KMT2AUSP2NPSR1ALDH1A1MAPT
SCHEMBL24908977 0.73 KMT2A (0.41) KMT2ATSHRPOLBALDH1A1YAP1
SCHEMBL24705091 0.73 LPAR1 (0.37) MAPK1KMT2ATSHRPOLBNPSR1
SCHEMBL24908947 0.73 LMNA (0.45) KMT2ATSHRPOLBALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed