SCHEMBL24909575

SCHEMBL24909575

C=N/C=C\C(=C/C)C(C(=O)NC1CCCCC1)N1C(=O)c2cc(Oc3ccc(C(C)(C)C)cc3)c3c4c(Oc5ccc(C(C)(C)C)cc5)cc5c6c(cc(Oc7ccc(C(C)(C)C)cc7)c(c7c(Oc8ccc(C(C)(C)C)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)NC1CCCCC1)c1ccncc1)C5=O

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
LMNA P02545 4/20 0.32
ALDH1A1 P00352 2/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 2/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
EPHX1 P07099 1/20 0.30
EPHX2 P34913 1/20 0.30
MDM2 Q00987 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
YAP1 P46937 1/20 0.30
BLM P54132 1/20 0.30
TEAD4 Q15561 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909196 0.88 MAPK1 (0.41) MAPK1ALDH1A1TSHRUSP2POLB
SCHEMBL24909039 0.74 EPHX2 (0.40) LMNAALDH1A1TSHRNPSR1KMT2A
SCHEMBL24909079 0.71 TSHR (0.46) MAPK1LMNAALDH1A1TSHRNPSR1
SCHEMBL24705443 0.68 KMT2A (0.34) KMT2AMAPT
SCHEMBL24908968 0.66 RAF1 (0.39) MAPK1LMNAALDH1A1HTTPOLB
SCHEMBL24908977 0.66 KMT2A (0.41) ALDH1A1HTTTSHRPOLBKMT2A
SCHEMBL24909227 0.65 TP53 (0.44) MAPK1LMNAALDH1A1TSHRPOLB
SCHEMBL24908687 0.65 LMNA (0.33) MAPK1LMNAHTTNPSR1MAPT
SCHEMBL24705146 0.65 CTSL (0.35) LMNAALDH1A1HTTNPSR1
SCHEMBL24705091 0.64 LPAR1 (0.37) MAPK1LMNAALDH1A1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed