SCHEMBL24909256

SCHEMBL24909256

CCCC(C(=O)Oc1ccncc1)N1C(=O)c2cc(Oc3ccc(C)cc3)c3c4c(Oc5ccc(C)cc5)cc5c6c(cc(Oc7ccc(C)cc7)c(c7c(Oc8ccc(C)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(CCC)C(=O)Oc1ccncc1)C5=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
P2RX3 P56373 4/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34
MMP13 P45452 2/20 0.33
GALR3 O60755 1/20 0.33
GAA P10253 1/20 0.33
MMP2 P08253 1/20 0.33
CYP3A4 P08684 1/20 0.33
STAT3 P40763 1/20 0.33
MAPK14 Q16539 1/20 0.33
HSD11B1 P28845 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909538 0.83 KMT2A (0.46) ALDH1A1MAPTKMT2APOLBHTT
SCHEMBL24908951 0.81 ALDH1A1 (0.43) ALDH1A1MAPTKMT2APOLBHTT
SCHEMBL24705206 0.81 POLB (0.36) ALDH1A1MAPTKMT2APOLBHTT
SCHEMBL24909317 0.80 ALDH1A1 (0.42) ALDH1A1MAPTKMT2APOLBHTT
SCHEMBL24705208 0.79 ALDH1A1 (0.38) ALDH1A1MAPTKMT2APOLB
SCHEMBL24908973 0.78 HSD11B1 (0.45) ALDH1A1MAPTKMT2APOLBHTT
SCHEMBL24908995 0.77 ALDH1A1 (0.42) ALDH1A1MAPTKMT2APOLBHTT
SCHEMBL24705091 0.77 LPAR1 (0.37) ALDH1A1MAPTKMT2APOLBHTT
SCHEMBL24705626 0.75 MCL1 (0.45) ALDH1A1MAPTKMT2APOLBLPAR1
SCHEMBL24909637 0.75 DNMT1 (0.44) ALDH1A1MAPTKMT2APOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed