SCHEMBL24909294

SCHEMBL24909294

CC(C)c1ccc(Oc2cc3c4c(cc(Oc5ccc(C(C)C)cc5)c5c6c(Oc7ccc(C(C)C)cc7)cc7c8c(cc(Oc9ccc(C(C)C)cc9)c(c2c45)c86)C(=O)N(C(Cc2ccc(O)cc2)C(=O)N(c2ccccc2)c2ccccc2)C7=O)C(=O)N(C(Cc2ccc(O)cc2)C(=O)N(c2ccccc2)c2ccccc2)C3=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.46
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.39
CYP2D6 P10635 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
AADAT Q8N5Z0 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
MAPT P10636 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MCL1 Q07820 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
BCL2L1 Q07817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909217 0.88 POLB (0.35) POLBKMT2ACYP2D6ALDH1A1GAA
SCHEMBL24908692 0.84 POLB (0.42) POLBKMT2AMEN1ALDH1A1GAA
SCHEMBL24909390 0.84 ALDH1A1 (0.40) POLBKMT2AALDH1A1GAAAADAT
SCHEMBL24909032 0.83 KMT2A (0.42) POLBKMT2AMEN1ALDH1A1GAA
SCHEMBL24909394 0.81 POLB (0.37) POLBKMT2AMEN1CYP2D6TDP1
SCHEMBL24909057 0.81 KMT2A (0.48) POLBKMT2AMEN1ALDH1A1GAA
SCHEMBL24908665 0.80 POLB (0.47) POLBKMT2AMEN1CYP2D6TDP1
SCHEMBL24739699 0.80 POLB (0.41) POLBKMT2AMEN1CYP2D6TDP1
SCHEMBL24908770 0.78 POLB (0.45) POLBKMT2AMEN1CYP2D6TDP1
SCHEMBL24909101 0.77 KMT2A (0.35) POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed
US-9624160-B2 Reactive ionic liquids BASF SE (DE) 2017-04-18 US disclosed