SCHEMBL24909394

SCHEMBL24909394

CCN(CC)C(=O)C(Cc1ccc(O)cc1)N1C(=O)c2cc(Oc3ccc(C(C)C)cc3)c3c4c(Oc5ccc(C(C)C)cc5C)cc5c6c(cc(Oc7ccc(C(C)C)cc7C)c(c7c(Oc8ccc(C(C)C)cc8C)cc(c2c37)C1=O)c64)C(=O)N(C(Cc1ccc(O)cc1)C(=O)N(CC)CC)C5=O

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.34
CYP2D6 P10635 1/20 0.34
MEN1 O00255 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LPAR1 Q92633 1/20 0.31
LPAR5 Q9H1C0 1/20 0.31
MCL1 Q07820 2/20 0.31
BCL2L1 Q07817 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909629 0.96 POLB (0.39) POLBKMT2ACYP2D6MEN1TDP1
SCHEMBL24909294 0.81 POLB (0.46) POLBKMT2ACYP2D6MEN1TDP1
SCHEMBL24908692 0.79 POLB (0.42) POLBKMT2AMEN1L3MBTL1MCL1
SCHEMBL24909390 0.79 ALDH1A1 (0.40) POLBKMT2AL3MBTL1
SCHEMBL24909633 0.78 MAPK1 (0.39) KMT2AMEN1BCHEACHEHSP90AA1
SCHEMBL24908761 0.77 TSHR (0.38) POLBKMT2AMEN1
SCHEMBL24909218 0.77 POLB (0.40) POLBKMT2ACYP2D6MEN1TDP1
SCHEMBL24704857 0.77 ALDH1A1 (0.44) POLBKMT2ACYP2D6MEN1TDP1
SCHEMBL24909307 0.76 POLB (0.54) POLBKMT2ACYP2D6MEN1TDP1
SCHEMBL24909200 0.75 ALDH1A1 (0.39) POLBKMT2ABCHEACHEL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed