SCHEMBL24909319

SCHEMBL24909319

Cc1ccc(Oc2cc3c4c(cc(Oc5ccc(C)cc5C)c5c6c(Oc7ccc(C)cc7C)cc7c8c(cc(Oc9ccc(C)cc9C)c(c2c45)c86)C(=O)N(C(Cc2ncc[nH]2)C(=O)N(c2ccccc2)c2ccccc2)C7=O)C(=O)N(C(Cc2ncc[nH]2)C(=O)N(c2ccccc2)c2ccccc2)C3=O)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
HIF1A Q16665 1/20 0.33
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CCKBR P32239 1/20 0.32
TAAR1 Q96RJ0 3/20 0.32
HSD11B1 P28845 1/20 0.31
DNMT1 P26358 2/20 0.30
CYP2C19 P33261 1/20 0.30
DNMT3B Q9UBC3 1/20 0.30
PKM P14618 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909050 0.83 KMT2A (0.34) HIF1ATSHRTAAR1HSD11B1DNMT1
SCHEMBL24909030 0.81 CETP (0.32) HIF1ATSHRGAA
SCHEMBL24909327 0.78 ALDH1A1 (0.31) KMT2A
SCHEMBL24909390 0.77 ALDH1A1 (0.40) TSHRL3MBTL1HSD11B1PKMKMT2A
SCHEMBL24909029 0.76 TRPM8 (0.34) TSHRMAPK1TAAR1HSD11B1CYP2C19
SCHEMBL24908704 0.76 NPC1 (0.35) TDP1HIF1AHPGDTSHRTAAR1
SCHEMBL24908966 0.76 TRPM8 (0.31)
SCHEMBL24909639 0.74 PTH1R (0.32)
SCHEMBL24908669 0.72 MCL1 (0.41) TDP1MAPK1GAA
SCHEMBL24909307 0.71 POLB (0.54) TDP1L3MBTL1HSD11B1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed