SCHEMBL24909334

SCHEMBL24909334

CSc1ccc(-c2cc(C#N)cc(Br)c2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.51
ALB P02768 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
SIRT1 Q96EB6 1/20 0.35
MAOA P21397 2/20 0.33
MAOB P27338 1/20 0.33
KDM1A O60341 1/20 0.33
AR P10275 1/20 0.33
MMP3 P08254 1/20 0.33
PTGS2 P35354 1/20 0.32
SLC22A12 Q96S37 3/20 0.32
XDH P47989 2/20 0.32
ALOX5 P09917 1/20 0.31
CTSK P43235 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909717 0.85 TTR (0.47) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909826 0.84 TTR (0.62) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909714 0.80 TTR (0.56) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909360 0.80 MEN1 (0.60) TTRALBMEN1KMT2AMAOA
SCHEMBL24909858 0.79 MEN1 (0.51) TTRALBMEN1KMT2AMAOA
SCHEMBL24909767 0.79 TTR (0.51) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909920 0.79 TTR (0.51) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909391 0.79 TTR (0.51) TTRALBMEN1KMT2ASIRT1
SCHEMBL24910063 0.78 TTR (0.53) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909854 0.77 TTR (0.51) TTRALBMEN1KMT2ASIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.