SCHEMBL24909360

SCHEMBL24909360

N#Cc1cc(Br)c(O)c(-c2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.60
TTR P02766 1/20 0.60
ALB P02768 1/20 0.60
KMT2A Q03164 1/20 0.60
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
MAPK1 P28482 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
METAP2 P50579 1/20 0.44
AKR1C3 P42330 2/20 0.42
AKR1C2 P52895 2/20 0.42
AKR1C1 Q04828 2/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
BACE1 P56817 1/20 0.41
AKR1C4 P17516 1/20 0.40
ALDH1A1 P00352 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909826 0.88 TTR (0.62) MEN1TTRALBKMT2AMAOA
SCHEMBL24909749 0.87 MEN1 (0.56) MEN1TTRALBKMT2ACRHBP
SCHEMBL24910032 0.85 MEN1 (0.55) MEN1TTRALBKMT2ACRHBP
SCHEMBL29936349 0.84 MEN1 (0.53) MEN1TTRALBKMT2ACRHBP
SCHEMBL23621220 0.84 MEN1 (0.53) MEN1TTRALBKMT2ACRHBP
SCHEMBL24909714 0.83 TTR (0.56) MEN1TTRALBKMT2AMAOA
SCHEMBL24909685 0.83 TTR (0.51) MEN1TTRALBKMT2AKDM4E
SCHEMBL24909835 0.83 MEN1 (0.51) MEN1TTRALBKMT2APTGDR2
SCHEMBL24910016 0.83 MEN1 (0.51) MEN1TTRALBKMT2AALDH1A1
SCHEMBL24909849 0.83 TTR (0.60) MEN1TTRALBKMT2ACRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885TTR 4497/4885ALB 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.