SCHEMBL24909714

SCHEMBL24909714

N#Cc1cc(Br)c(O)c(-c2ccc(F)cc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.56
ALB P02768 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
PTGS1 P23219 1/20 0.42
SIRT1 Q96EB6 1/20 0.40
GCGR P47871 1/20 0.38
MAPK14 Q16539 1/20 0.38
IL4 P05112 1/20 0.35
MMP3 P08254 1/20 0.35
RPS6KA3 P51812 1/20 0.35
KDM1A O60341 1/20 0.35
MAOA P21397 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
XDH P47989 3/20 0.34
SLC22A12 Q96S37 3/20 0.34
CYP2C8 P10632 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909826 0.88 TTR (0.62) TTRALBMEN1KMT2APTGS1
SCHEMBL24909370 0.87 TTR (0.60) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909730 0.85 TTR (0.58) TTRALBMEN1KMT2A
SCHEMBL24909772 0.84 TTR (0.53) TTRALBMEN1KMT2ASIRT1
SCHEMBL29936349 0.84 MEN1 (0.53) TTRALBMEN1KMT2AADORA2A
SCHEMBL23621220 0.84 MEN1 (0.53) TTRALBMEN1KMT2AADORA2A
SCHEMBL24909360 0.83 MEN1 (0.60) TTRALBMEN1KMT2AMAOA
SCHEMBL24910027 0.83 KIF11 (0.51) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909854 0.83 TTR (0.51) TTRALBMEN1KMT2ASIRT1
SCHEMBL24909769 0.82 TTR (0.50) TTRALBMEN1KMT2AKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.