SCHEMBL24909685

SCHEMBL24909685

Cc1cccc(-c2cc(C#N)cc(Br)c2O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.51
ALB P02768 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ADORA2A P29274 2/20 0.40
ADORA1 P30542 2/20 0.40
ACHE P22303 1/20 0.38
LRRK2 Q5S007 2/20 0.38
AR P10275 1/20 0.38
RPS6KA3 P51812 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
CNR2 P34972 2/20 0.37
CNR1 P21554 1/20 0.37
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
ADORA2B P29275 1/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909749 0.86 MEN1 (0.56) TTRALBMEN1KMT2ACNR2
SCHEMBL24910032 0.85 MEN1 (0.55) TTRALBMEN1KMT2AADORA2A
SCHEMBL23621220 0.84 MEN1 (0.53) TTRALBMEN1KMT2AADORA2A
SCHEMBL29936349 0.84 MEN1 (0.53) TTRALBMEN1KMT2AADORA2A
SCHEMBL24909360 0.83 MEN1 (0.60) TTRALBMEN1KMT2AKDM4E
SCHEMBL24909835 0.82 MEN1 (0.51) TTRALBMEN1KMT2AADORA2A
SCHEMBL24909717 0.82 TTR (0.47) TTRALBMEN1KMT2ACNR2
SCHEMBL24909705 0.82 TTR (0.47) TTRALBMEN1KMT2AALOX15
SCHEMBL24910063 0.81 TTR (0.53) TTRALBMEN1KMT2AAR
SCHEMBL24910068 0.79 TTR (0.51) TTRALBMEN1KMT2ALRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.