Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24909913 | 0.86 | KDM4E (0.46) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL24909936 | 0.84 | NPSR1 (0.44) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL24910077 | 0.82 | KDM4E (0.42) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL28838740 | 0.77 | KDM4E (0.48) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL29587732 | 0.77 | FASN (0.45) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL18617426 | 0.77 | FASN (0.45) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL24909797 | 0.76 | KDM4E (0.43) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL23621220 | 0.74 | MEN1 (0.53) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL29936349 | 0.74 | MEN1 (0.53) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL24909840 | 0.74 | ACLY (0.44) | KDM4EHPGDNPSR1RXFP1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024283-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024283-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | KDM4E 865/4885HPGD 1770/4885NPSR1 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.