Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 5/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18617426 | 1.00 | FASN (0.45) | FASNCYP11B2KDM4EHPGDNPSR1 | |
| SCHEMBL18617407 | 0.83 | CNR1 (0.47) | FASNCYP11B2KDM4EHPGDCNR1 | |
| SCHEMBL18587347 | 0.82 | MAOA (0.53) | FASNKDM4EHPGDNPSR1CNR1 | |
| SCHEMBL28838740 | 0.82 | KDM4E (0.48) | KDM4EHPGDNPSR1RXFP1ESR2 | |
| SCHEMBL29430616 | 0.81 | MAP4K4 (0.43) | FASNCYP11B2KDM4EHPGDNPSR1 | |
| SCHEMBL24909443 | 0.77 | KDM4E (0.44) | FASNCYP11B2KDM4EHPGDNPSR1 | |
| SCHEMBL18587789 | 0.77 | CTSS (0.43) | FASNKDM4ECNR2MAOAMAOB | |
| SCHEMBL18617449 | 0.77 | CA3 (0.40) | FASNCYP11B2CNR1CNR2ESR2 | |
| SCHEMBL29587766 | 0.77 | CA3 (0.40) | FASNCYP11B2CNR1CNR2ESR2 | |
| SCHEMBL5098919 | 0.76 | MAOA (0.48) | CYP11B2KDM4EHPGDNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | CNKSR1, RB1, RCOR1 | FASN 3999/4885CYP11B2 419/4885KDM4E 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.