SCHEMBL24909705

SCHEMBL24909705

CC(C)c1cccc(-c2cc(C#N)cc(Br)c2O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.47
ALB P02768 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
RXRA P19793 2/20 0.38
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
NR4A2 P43354 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
KDM4E B2RXH2 1/20 0.36
MDM4 O15151 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
TYR P14679 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909982 0.89 TTR (0.47) TTRALBMEN1KMT2AKDM4E
SCHEMBL24909767 0.85 TTR (0.51) TTRALBMEN1KMT2AMAPT
SCHEMBL24909749 0.83 MEN1 (0.56) TTRALBMEN1KMT2APTPN5
SCHEMBL24909685 0.82 TTR (0.51) TTRALBMEN1KMT2AKDM4E
SCHEMBL24910032 0.81 MEN1 (0.55) TTRALBMEN1KMT2ACTSS
SCHEMBL24909867 0.81 MEN1 (0.44) TTRALBMEN1KMT2ARXRA
SCHEMBL29936349 0.80 MEN1 (0.53) TTRALBMEN1KMT2AKDM4E
SCHEMBL23621220 0.80 MEN1 (0.53) TTRALBMEN1KMT2AKDM4E
SCHEMBL24909360 0.79 MEN1 (0.60) TTRALBMEN1KMT2AKDM4E
SCHEMBL24909835 0.79 MEN1 (0.51) TTRALBMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.