SCHEMBL24909701

SCHEMBL24909701

COc1cc(-c2cc(C#N)cc(Br)c2O)cc(Cl)n1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.44
ALB P02768 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GRM5 P41594 3/20 0.34
RECQL P46063 1/20 0.31
EGFR P00533 1/20 0.31
ADORA2A P29274 1/20 0.30
LCK P06239 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909921 0.87 TTR (0.55) TTRALBMEN1KMT2AGRM5
SCHEMBL24909750 0.83 TTR (0.47) TTRALBMEN1KMT2AGRM5
SCHEMBL24909894 0.82 MEN1 (0.41) TTRALBMEN1KMT2A
SCHEMBL24909929 0.78 TTR (0.55) TTRALBMEN1KMT2AGRM5
SCHEMBL24909892 0.77 MEN1 (0.46) TTRALBMEN1KMT2A
SCHEMBL24909733 0.77 TTR (0.46) TTRALBMEN1KMT2AGRM5
SCHEMBL24909706 0.75 TTR (0.58) TTRALBMEN1KMT2AGRM5
SCHEMBL11296944 0.74 GRM5 (0.51) GRM5RECQL
SCHEMBL24909858 0.73 MEN1 (0.51) TTRALBMEN1KMT2ALCK
SCHEMBL24910024 0.73 TTR (0.55) TTRALBMEN1KMT2AGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.