SCHEMBL24909894

SCHEMBL24909894

COc1cc(-c2cc(C#N)cc(Br)c2O)cc(C(F)(F)F)n1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
TTR P02766 1/20 0.41
ALB P02768 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909701 0.82 TTR (0.44) MEN1TTRALBKMT2A
SCHEMBL24909846 0.76 MEN1 (0.45) MEN1TTRALBKMT2AGABRA1
SCHEMBL24909929 0.76 TTR (0.55) MEN1TTRALBKMT2A
SCHEMBL24909721 0.75 CYP1A2 (0.35) MEN1KMT2AKDM4E
SCHEMBL24909859 0.75 MEN1 (0.44) MEN1TTRALBKMT2A
SCHEMBL24909892 0.74 MEN1 (0.46) MEN1TTRALBKMT2A
SCHEMBL24909724 0.73 TTR (0.51) MEN1TTRALBKMT2AGABRA1
SCHEMBL24910024 0.73 TTR (0.55) MEN1TTRALBKMT2AKDM4E
SCHEMBL24910000 0.73 TTR (0.47) MEN1TTRALBKMT2A
SCHEMBL24909370 0.71 TTR (0.60) MEN1TTRALBKMT2AGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885TTR 4497/4885ALB 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.