SCHEMBL2490973

SCHEMBL2490973

Cc1nc2ccc3ccccc3c2o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.58
ALDH1A1 P00352 5/20 0.58
KDM4E B2RXH2 3/20 0.58
MEN1 O00255 3/20 0.58
HPGD P15428 2/20 0.58
HSD17B10 Q99714 2/20 0.58
MAPT P10636 2/20 0.58
GAA P10253 2/20 0.58
NPC1 O15118 1/20 0.58
TP53 P04637 1/20 0.58
ALOX15 P16050 1/20 0.58
ALOX12 P18054 1/20 0.58
MPI P34949 1/20 0.58
HTT P42858 1/20 0.58
RAB9A P51151 1/20 0.58
ELANE P08246 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.44
CYP3A4 P08684 1/20 0.42
CYP2A6 P11509 4/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728164 1.00 KMT2A (0.58) KMT2AALDH1A1KDM4EMEN1HPGD
Iodide SCHEMBL30772927 0.98 KMT2A (0.57) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL26217310 0.87 KMT2A (0.48) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL17281452 0.83 ELANE (0.48) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL18133627 0.81 ELANE (0.47) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL20669007 0.81 ELANE (0.47) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL30773494 0.76 ELANE (0.52) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL29948066 0.76 CYP3A4 (0.42) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL18549019 0.76 ELANE (0.52) KMT2AALDH1A1KDM4EMEN1HPGD
SCHEMBL2517690 0.76 CYP3A4 (0.42) KMT2AALDH1A1KDM4EMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7566707-B2 Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-07-28 US claimed
EP-1641799-B1 IMIDAZO-PYRIDAZINONE DERIVATIVES AND IMIDAZO-PYRIDONE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM INT (DE) 2008-03-12 EP claimed
US-20050026921-A1 New imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-02-03 US claimed
US-20250312504-A1 VOLATILE COMPOSITION DISPENSER FOR COMPOSITIONS COMPRISING A META-(C1-C4 ALKOXY) SALICYLALDEHYDE THE PROCTER & GAMBLE COMPANY 2025-10-09 US disclosed
US-20240401112-A1 NOVEL COMPOUNDS AND THEIR APPLICATIONS SFC CO., LTD. (KR) 2024-12-05 US disclosed
US-20240199997-A1 COMPOSITIONS COMPRISING A META-(C1-C4 ALKOXY) SALICYLALDEHYDE PROCTER & GAMBLE COMPANY, THE 2024-06-20 US disclosed
CN-114874153-B Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2023-11-17 CN disclosed
US-11737353-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-08-22 US disclosed
WO-2023153739-A1 NOVEL COMPOUND AND USES THEREOF 에스에프씨 주식회사 2023-08-17 WO disclosed
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-30 US disclosed
EP-4006025-A1 HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-01 EP disclosed
US-7566707-B2 Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-07-28 US disclosed
US-7173152-B2 One-pot reductive acetamidation of aryl nitro compounds THE TEXAS A&M UNIVERSITY SYSTEM (US) 2007-02-06 US disclosed
US-7173152-B2 One-pot reductive acetamidation of aryl nitro compounds THE TEXAS A&M UNIVERSITY SYSTEM (US) 2007-02-06 US disclosed
US-20050026921-A1 New imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-02-03 US disclosed
US-6747159-B2 USING CYANINE COMPOUND VISEN MEDICAL, INC. 2004-06-08 US disclosed
US-6610468-B2 Naphthoxazole and thiazole derivative FUJI PHOTO FILM CO., LTD. (JP) 2003-08-26 US disclosed
US-20020156288-A1 Symmetric, monofunctionalised polymethine dyes labelling reagents VISEN MEDICAL, INC. 2002-10-24 US disclosed
US-20020051950-A1 Silver halide photographic material FUJIFILM CORPORATION (JP) 2002-05-02 US disclosed
US-4460779-A Method for preparing 2-lower alkyl-substituted naphthoxazoles by way of non-toxic intermediates MINNESOTA MINING & MANUFACTURING COMPANY (US) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156288-A1 Symmetric, monofunctionalised polymethine dyes labelling reagents H1-0, H1-3, H1-2 KMT2A 802/4885ALDH1A1 2182/4885KDM4E 2070/4885
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME EML4, STOM, GJB2 KMT2A 1066/4885ALDH1A1 2548/4885KDM4E 1381/4885
US-20050026921-A1 New imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions DPP4, DPP3, DPP7 KMT2A 2813/4885ALDH1A1 239/4885KDM4E 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.