SCHEMBL24909770

SCHEMBL24909770

N#Cc1cc(Br)c(O)c(-c2ccsc2Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.51
ALB P02768 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34
XDH P47989 4/20 0.34
SLC22A12 Q96S37 4/20 0.34
CYP2A6 P11509 1/20 0.33
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909901 0.81 TTR (0.50) TTRALBMEN1KMT2AGABRA1
SCHEMBL24909753 0.79 TRPV4 (0.37) XDHSLC22A12CYP2A6PTGS1
SCHEMBL24909889 0.76 KMT2A (0.55) TTRALBMEN1KMT2AGABRA1
SCHEMBL24909740 0.75 TTR (0.53) TTRALBMEN1KMT2AGABRA1
SCHEMBL24909844 0.75 MEN1 (0.53) TTRALBMEN1KMT2A
SCHEMBL24909847 0.73 KMT2A (0.51) TTRALBMEN1KMT2AGABRA1
SCHEMBL24909849 0.73 TTR (0.60) TTRALBMEN1KMT2AGABRA1
SCHEMBL24909706 0.72 TTR (0.58) TTRALBMEN1KMT2AGABRA1
SCHEMBL24909780 0.72 TTR (0.53) TTRALBMEN1KMT2AXDH
SCHEMBL24909826 0.71 TTR (0.62) TTRALBMEN1KMT2AGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.