SCHEMBL24909780

SCHEMBL24909780

N#Cc1cc(Br)c(O)c(-c2ccsc2)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.53
ALB P02768 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
TMIGD3 P0DMS9 2/20 0.36
ADORA2A P29274 2/20 0.36
ADORA1 P30542 2/20 0.36
SCN9A Q15858 1/20 0.36
PELI1 Q96FA3 2/20 0.35
LRRK2 Q5S007 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP2A6 P11509 1/20 0.34
ERN1 O75460 2/20 0.33
MAOB P27338 1/20 0.33
KDM1A O60341 1/20 0.32
PDE3A Q14432 1/20 0.32
XDH P47989 2/20 0.32
SLC22A12 Q96S37 2/20 0.32
ACMSD Q8TDX5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909826 0.79 TTR (0.62) TTRALBMEN1KMT2AMAOB
SCHEMBL24909404 0.78 TMIGD3 (0.36) TMIGD3ADORA2AADORA1SCN9APELI1
SCHEMBL24909360 0.78 MEN1 (0.60) TTRALBMEN1KMT2AALDH1A1
SCHEMBL24909749 0.75 MEN1 (0.56) TTRALBMEN1KMT2AMAOB
SCHEMBL24909714 0.75 TTR (0.56) TTRALBMEN1KMT2AADORA2A
SCHEMBL24910016 0.75 MEN1 (0.51) TTRALBMEN1KMT2AALDH1A1
SCHEMBL24909370 0.74 TTR (0.60) TTRALBMEN1KMT2ALRRK2
SCHEMBL24910032 0.74 MEN1 (0.55) TTRALBMEN1KMT2AADORA2A
SCHEMBL24909706 0.73 TTR (0.58) TTRALBMEN1KMT2AERN1
SCHEMBL24909730 0.73 TTR (0.58) TTRALBMEN1KMT2ALRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.